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Health-care facilities typically use isolation as a strategy for dealing with infection control, creating buildings that work as sets of departments closed off from one another.

NewYork-Presbyterian Hospital’s dense web of mostly older buildings at its 20-acre campus in Upper Manhattan is not unusual for medical complexes constructed over many decades.

Client: Northwest Community Healthcare Completion Date: May 2010 Program: An eight-story, 225,000-square-foot addition to the hospital, with an 11,000-square-foot lobby, an emergency department, intensive care, private patient rooms, and medical/surgical and perinatal units. Design Concept and Solution: The architects sought to enhance both the safety and privacy of patients while standardizing rooms for ease of care. The triangular form of the tower—whose sharp tip stands in counterpoint to the hospital's International Style campus—shortens travel distances for staff. To boost efficiency and flexibility, each room is a standard size, with a consistent layout, and is equipped to serve intensive-care patients and

In designing St. Anthony, a privately funded hospital in the wooded area outside Seattle, the architects at Zimmer Gunsul Frasca (ZGF) asked themselves, “What would you want to see in a five-star hotel?” says ZGF interior designer, Anita Rossen.

Completion Date: April 2009 Owner: Toraya Program: A new building for the Japanese pastry maker Toraya, which has occupied the site for approximately 500 years. The structure—housing a café, a gallery, offices, and the pastry workshop—is connected by a central garden to a small storage house from the Edo Period, for a total of 12,000 square feet. Design concept and solution: The architects wanted the café and garden-side terrace to feel like one big indoor-outdoor space, open and relaxing. They united the café and terrace with a gently sloping ceiling of narrow wood ribs, which extends into an awning over the

Built on an isthmus between Puget Sound and Lake Washington, Seattle boasts a history of fishing and nautical trade.

Using a process of renovation through subtraction, the New York—based firm Lynch / Eisinger / Design (L/E/D) created a multitenant commercial building in part by taking away pieces of an old industrial complex.

Completion Date: October 2009 Owner: Scottish Widows Program: A mixed-use revitalization of three buildings on a London block, anchored by two office buildings for the investment firm Scottish Widows. At 58,534 square feet, the New Bond Street office consists of five stories added to existing street-level retail space. The five-story St George Street office contributes another 62,926 square feet. Sandwiched between the offices, on Maddox Street, is a luxury residential building with ground-floor retail space; Eric Parry Architects refurbished the 18 apartments above. The development also includes a central courtyard shared by the three buildings. Design concept and solution: Retaining

A two-story, 144,217-square-foot retail grocery store, with a café, a community room, offices, staff facilities, underground parking, a warehouse, and a full commercial kitchen serving this store and Berkeley Bowl's Oregon Street location.